Table 2.
Blood Pressure and Metabolic Variables in the 2 Subgroups of Former Patients and in the Parous Controls at 1-Year and 14-Year Postpartum With the Absolute Change Accumulated in the Intermeasurement Interval.a
| Controls | NT-exPE | HT-exPE | Overall P Value | P Value NT-exPE Vs HT-exPE | ||
|---|---|---|---|---|---|---|
| (n = 8) | (n = 13) | (n = 7) | ||||
| BMI, kg/m2 | 1-Year pp | 20.8 (19.4; 24.9) | 21.8 (20.4; 24.7) | 24.1 (18.9; 28.7) | .59 | .49 |
| 14-Year pp | 22.5 (20.3; 26.5) | 23.6 (22.5; 25.8) | 27.9 (23.0; 29.2) | .12 | .08 | |
| Diff | 1.4 (−0.1; 3.0) | 2.1 (0.8; 3.3) | 2.7 (1.5; 5.9) | .34 | .31 | |
| Weight, kg | 1-Year pp | 59 (54; 64) | 62 (59; 67) | 69 (55; 74) | .33 | .59 |
| 14-Year pp | 62 (57; 70) | 68 (61; 76) | 76 (69; 87) | .06 | .16 | |
| Diff | 3 (0; 6) | 5 (2; 8) | 7 (5; 13) | .22 | .21 | |
| Systolic BP, mm Hg | 1-Year pp | 117 (108; 126) | 115 (110; 121) | 128 (120; 140)b | <.05 | <.01 |
| 14-Year pp | 128 (110; 146) | 114 (112; 129) | 152 (138; 159)b | <.01 | <.01 | |
| Diff | 11 (−1; 30) | −2 (−8; 6) | 16 (−2; 29)b | .08 | <.01 | |
| Diastolic BP, mm Hg | 1-Year pp | 75 (69; 78) | 69 (64; 74) | 85 (75; 91)b,c | <.01 | <.01 |
| 14-Year pp | 78 (68; 81) | 72 (63; 79) | 92 (90; 99)b,c | <.01 | <.01 | |
| Diff | 3 (−3; 11) | −2 (−7; 6) | −1 (−3; 10) | .49 | .35 | |
| MAP, mm Hg | 1-Year pp | 91 (79; 95) | 84 (79; 89) | 98 (88; 112)b,c | <.05 | <.01 |
| 14-Year pp | 97 (85; 104) | 88 (80; 98) | 114 (107; 121)b,c | <.01 | <.01 | |
| Diff | 10 (3; 18) | 1 (−5; 8) | 5 (0; 20) | .31 | .24 | |
| Pulse pressure, mm Hg | 1-Year pp | 42 (40; 50) | 46 (44; 50) | 45 (39; 49) | .27 | .39 |
| 14-Year pp | 48 (40; 68) | 48 (43; 55) | 57 (54; 61)b,c | .09 | <.05 | |
| Diff | 8 (−2; 22) | 2 (−6; 6) | 8 (6; 21)b | <.05 | <.01 | |
| Glucose, mmol·L−1 | 1-Year pp | 4.8 (4.5; 5.4) | 4.8 (4.0; 5.7) | 4.9 (4.2; 5.8) | .94 | .70 |
| 14-Year pp | 5.2 (4.9; 5.5) | 5.1 (5.0; 5.4) | 5.3 (5.3; 5.7) | .27 | .11 | |
| Diff | 0.6 (0.0; 0.7) | 0.3 (0.0; 0.8) | 0.5 (0.2; 1.1) | .84 | .64 | |
| Insulin, mU·L−1 | 1-Year pp | 6.1 (3.8; 10.2) | 6.8 (4.2; 8.1) | 8.7 (7.9; 13.9)b | .10 | <.01 |
| 14-Year pp | 5.5 (2.0; 8.9) | 5.5 (3.0; 8.3) | 8.9 (6.2; 14.0) | .14 | <.05 | |
| Diff | −2.1 (−3.4; 0.3) | −0.6 (−3.1; 1.7) | 0.2 (−7.2; 6.1) | .67 | .76 | |
| Cholesterol, mmol·L−1 | 1-Year pp | 4.7 (4.5; 6.0) | 5.2 (4.6; 5.8) | 4.5 (4.1; 6.1) | .65 | .59 |
| 14-Year pp | 5.0 (4,2; 5.7) | 4.8 (4.3; 5.9) | 5.0 (4.6; 5.5) | .96 | .76 | |
| Diff | 0.3 (−0.7; 1.1) | −0.2 (−0.6; 0.7) | 0.7 (−0.7; 1.0) | .72 | .44 | |
| HDL-cholesterol, mmol·L−1 | 1-Year pp | 1.6 (1.2; 1.9) | 1.6 (1.2; 1.7) | 1.2 (0.8; 1.3) | .17 | .10 |
| 14-Year pp | 1.1 (1.0; 1.6) | 1.3 (1.2; 1.5) | 0.8 (0.7; 1.3) | .14 | .06 | |
| Diff | −0.3 (−0.7; 0.2) | −0.2 (−0.4; 0.1) | −0.1 (−0.5; 0.3) | .64 | .88 | |
| LDL-cholesterol, mmol·L−1 | 1-Year pp | 2.4 (2.3; 2.9) | 3.8 (2.8; 4.4)c | 2.8 (2.4; 3.0) | <.05 | .08 |
| 14-Year pp | 3.2 (2.4; 3.8) | 3.0 (2.7; 3.9) | 3.0 (3.0; 3.7) | .91 | 1.00 | |
| Diff | 0.8 (−0.1; 1.3) | 0.0 (−0.9; 0.2) | 0.4 (0.1; 0.7) | .06 | .06 | |
| Triglycerides, mmol·L−1 | 1-Year pp | 0.9 (0.6; 1.0) | 1.2 (0.8; 1.3) | 1.2 (0.8; 1.7) | .13 | .49 |
| 14-Year pp | 1.1 (0.8; 1.7) | 0.7 (0.5; 0.8)c | 1.6 (1.3; 2.1)b | <.01 | <.05 | |
| Diff | 0.1 (−0.1; 0.9) | −0.3 (−0.7; 0.1)c | 0.5 (0.0; 0.9) | <.05 | .08 | |
Abbreviations: BP, blood pressure; BMI, body mass index; PE, preeclampsia; NT, normotensive; HT, hypertensive; BMI, body mass index; HOMA, Homeostatic Model Assessment; HDL, high-density lipoprotein; LDL, low-density lipoprotein; Diff, difference between 1-year and 14-year postpartum; MAP, mean arterial pressure; exPE, former preeclampsia; IQR, interquartile range; pp, postpartum; N, number.
a Data are presented as median with IQR or N with %.
b P < .05 compared with NT-exPE.
c P < .05 compared with controls.