Table 3.
Cardiac Indices in the 2 Subgroups of exPE Women and in the Control Group Observed at 1-Year and 14-Year Postpartum With the Absolute Change Accumulated in the Intermeasurement Interval.a
| Controls | NT-exPE | HT-exPE | P Value NT-exPE | |||
|---|---|---|---|---|---|---|
| (n = 8) | (n = 13) | (n = 7) | Overall P Value | Vs HT-exPE | ||
| Cardiac geometry | ||||||
| LAD, mm | 1-Year pp | 34 (32; 36) | 36 (32; 37) | 36 (34; 36) | .67 | .88 |
| 14-Year | 35 (31; 41) | 34 (33; 37) | 37 (34; 40) | .47 | .24 | |
| Diff | 1 (−3; 4) | 0 (−3; 2) | 0 (−2; 3) | .83 | .58 | |
| IVST, mm | 1-Year pp | 7.0 (7.0; 8.0) | 7.0 (7.0; 8.0) | 7.0 (7.0; 8.0) | .92 | .92 |
| 14-Year pp | 8.0 (7.6; 8.8) | 7.4 (7.1; 7.8)a | 8.3 (7.8; 9.0)b | <.01 | <.01 | |
| Diff | 1.0 (0.6; 1.2) | 0.1 (−0.3; 0.5)a | 1.0 (0.5; 1.3)b | <.01 | <.01 | |
| PWT, mm | 1-Year pp | 8.0 (7.0; 8.0) | 8.0 (7.0; 8.0) | 8.0 (7.0; 8.0) | .77 | .70 |
| 14-Year pp | 7.7 (7.0; 7.9) | 7.1 (6.8; 7.9) | 8.3 (8.0; 9.1)a,b | <.01 | <.01 | |
| Diff | −0.2 (−0.9; 0.3) | −0.3 (−1.0; −0.1) | 0.9 (0.2; 1.1)a,b | <.01 | <.01 | |
| LV-mass, g | 1-Year pp | 122 (114; 144) | 134 (127; 146) | 134 (106; 168) | .83 | .88 |
| 14-Year pp | 110 (105; 139) | 115 (95; 140) | 126 (117; 178) | .18 | .08 | |
| Diff | −13 (−16; −1) | −15 (−27; −5) | 11 (−17; 21) | .23 | .08 | |
| LV-mass index, g·m−2.7 | 1-Year pp | 31 (29; 38) | 32 (28; 38) | 33 (25; 38) | 1.00 | 1.00 |
| 14-Year pp | 29 (26; 35) | 28 (24; 34) | 29 (28; 44) | .18 | .12 | |
| Diff | −3 (−4; −1) | −5 (−8; 0) | 4 (−5; 6)b | .13 | <.05 | |
| RWT, ∼ | 1-Year pp | 0.32 (0.30; 0.37) | 0.33 (0.31; 0.34) | 0.33 (0.32; 0,38) | .62 | .54 |
| 14-Year pp | 0.35 (0.32; 0.36) | 0.31 (0.30; 0.32)a | 0.34 (0.33; 0.40)b | <.01 | <.05 | |
| Diff | 0.01 (−0.04; 0.04) | −0.01 (−0.03; −0.00) | 0.02 (−0.03; 0.05) | .13 | .08 | |
| LVEDD, mm | 1-Year pp | 45 (42; 47) | 46 (44; 48) | 46 (40; 48) | .88 | .88 |
| 14-Year pp | 44 (42; 49) | 46 (45; 50) | 47 (45; 53) | .24 | .94 | |
| Diff | 1 (−2; 3) | 1 (−1; 4) | 3 (−2; 7) | .48 | .88 | |
| LVESD, mm | 1-Year pp | 30 (27; 30) | 30 (28; 32) | 27 (26; 32) | .32 | .27 |
| 14-Year pp | 30 (28; 33) | 32 (30; 33) | 30 (29; 34) | .52 | .64 | |
| Diff | 2 (0; 3) | 1 (0; 4) | 2 (1; 6) | .59 | .35 | |
| Hemodynamic variables | ||||||
| EF, % | 1-Year pp | 67 (64; 69) | 62 (61; 65) | 68 (62; 72) | .06 | .08 |
| 14-Year pp | 61 (58; 65) | 62 (58; 65) | 65 (59; 66) | .46 | .27 | |
| Diff | −5 (−8; −2) | −1 (−6; 1) | −5 (−8; 2) | .26 | .35 | |
| EA ratio | 1-Year pp | 1.7 (1.5; 2.0) | 1.6 (1.3; 2.1) | 1.4 (1.3; 1.7) | .36 | .31 |
| 14-Year pp | 1.2 (1.1; 1.3) | 1.4 (1.3; 1.5) | 1.0 (1.0; 1.2)b | <.05 | <.05 | |
| Diff | −0.3 (−0.6; −0.2) | −0.4 (−0.7; 0.07) | −0.15 (−0.7; 0.0) | .77 | .94 | |
| SV, mL | 1-Year pp | 69 (62; 74) | 75 (71; 81) | 73 (65; 75) | .08 | .16 |
| 14-Year pp | 70 (65; 83) | 75 (69; 83) | 77 (66; 104) | .47 | .44 | |
| Diff | 3 (−2; 9) | −5 (−9; 3) | 11 (1; 31) | .06 | .06 | |
| CO, L·min−1 | 1-Year pp | 4.7 (4.4; 5.1) | 5.4 (4.7; 5.7) | 5.4 (4.8; 6.2) | .16 | .49 |
| 14-Year pp | 4.4 (4.0; 5.0) | 4.3 (4.2; 4.9) | 5.8 (4.5; 7.0)a,b | <.05 | <.05 | |
| Diff | −0.2 (−0.8; 0.2) | −0.6 (−1.4; −0.3) | 0.7 (−1.1; 2.2) | .12 | .12 | |
| CI, L·min−1·m−2 | 1-Year pp | 2.9 (2.7; 3.2) | 3.3 (2.7; 3.4) | 3.0 (2.9; 3.5) | .48 | .76 |
| 14-Year pp | 2.6 (2.3; 3.2) | 2.5 (2.4; 2.8) | 3.1 (2.6; 3.3) | .17 | <.05 | |
| Diff | −0.2 (−0.6; 0.0) | −0.4 (−0.9; −0.3) | 0.2 (−0.7; 0.9) | .33 | .18 | |
Abbreviations: PE, preeclampsia; NT, normotensive; HT, hypertensive; LAD, left atrium diameter; IVST, interventricular septum thickness; PWT, posterior wall thickness; LV-mass, left ventricular mass; LV-mass index; RWT, relative wall thickness; EF, ejection fraction; SV, stroke volume; CO, cardiac output; CI, cardiac index; LVEDD, left ventricular end-diastolic diameter; LVESD, left ventricular end-systolic diameter; Diff, difference between 1-year and 14-year pp; IQR, interquartile range; exPE, former preeclampsia; pp, postpartum.
a Data are presented as median with IQR.
b P < .05 compared with controls.
c P < .05 compared with NT-exPE.