Proposed scheme for potential targets for the prevention of postoperative adhesion development. ↑ denotes an increase; ↓, a decrease; Cl−, chloride ion; Fe+2 and Fe+3, elemental iron; GSH, glutathione; GSSG, glutathione disulfide; H2O, water; H4B, tetrahydrobiopterin; H2O2, hydrogen peroxide; HOCI, hypochlorous acid; l-Arg, l-arginine; MPO, myeloperoxidase; O2, molecular oxygen; O2
•–, superoxide anion; HO•, hydroxyl radical; ONOO−, peroxynitrite; NADPH, nicotine adenine dinucleotide phosphate; NO, nitric oxide; NO2
−, nitrite; NO3
−, nitrate; iNOS, inducible nitric oxide synthase; ROS, reactive oxygen species; SOD, superoxide dismutase; TGF-β, transforming growth factor β; XO, xanthine oxidase; XDH, xanthine dehydrogenase.