Table 4.
Comparison between IMRT and VMAT for 38 cervical and endometrial plans
| IMRT (n = 38) | 1A (n = 38) | 1Am (n = 38) | 2A (n = 38) | 2Am (n = 38) | |
|---|---|---|---|---|---|
|
PTV |
|
|
|
|
|
| Dmax (%) |
109.9 (106.7 - 113.5) |
110.2 (107.4 - 117.3)b+ |
111.3 (107.4- 117.3)ac+ |
109.3 (106.2 - 115.2)ab+ |
109.4 (106.2 - 113.0)c+ |
| V95% (%) |
96.2 (89.5 - 98.7) |
92.6 (86.8 - 96.3)a+b+ |
91.9 (83.2 - 96.3)a+c+ |
95.2 (90.6 - 98.4)a+b+ |
95.2 (89.4 - 98.4)a+c+ |
| HI |
1.09 (1.07 - 1.13) |
1.11 (1.09 - 1.16)a+b+ |
1.12 (1.09 - 1.18)a+c+ |
1.09 (1.07 - 1.13)b+ |
1.09 (1.07 - 1.14)c+ |
| CN |
0.77 (0.65 - 0.89) |
0.79 (0.65 - 0.86)b+ |
0.77 (0.62 - 0.85)c+ |
0.83 (0.71 - 0.89)a+b+ |
0.83 (0.68 - 0.89)a+c+ |
|
Body |
|
|
|
|
|
| Dmean (Gy) |
13.8 (9.1 - 19.3) |
13.1 (8.3 - 17.5)a+ |
13.2 (8.3 - 17.9)a+c |
13.0 (8.3 - 17.6)a+b |
13.1 (8.3 - 18.2)a+c |
| V 5Gy (%) |
54.6 (37.4 - 70.6) |
55.9 (39.1 - 69.8)a+b |
56.1 (39.2 - 69.6)a+ |
56.1 (39.5 - 70.1)a+ |
56.1 (39.5 - 70.4)a+ |
|
Rectum |
|
|
|
|
|
| V40 Gy (%) |
42.3 (0.1 - 100.0) |
43.9 (0.9 - 100.0) |
43.7 (0.1 - 100.0) |
44.0 (0.3 - 100.0) |
43.3 (0.7 - 100.0) |
| Dmax (Gy) |
46.9 (41.1 - 49.6) |
47.2 (43.8 - 48.8)b+ |
47.2 (42.2 - 49.3)c+ |
46.8 (41.7 - 48.1)b+ |
46.8 (42.0 - 48.7)c+ |
|
Bladder |
|
|
|
|
|
| V40 Gy (%) |
44.7 (7.4 - 100.0) |
44.2 (8.6 - 100.0) |
43.7 (8.4 - 99.6) |
43.8 (6.5 - 100.0) |
43.5 (9.4 - 100.0) |
| Dmax (Gy) |
48.2 (46.3 - 49.6) |
47.8 (46.3 - 49.4)a+b+ |
48.1 (46.3 - 50.6)c+ |
47.3 (44.1 - 48.9)a+b+ |
47.4 (44.4 - 49.8)a+c+ |
|
Small Intestine |
|
|
|
|
|
| V45 Gy (ccm) |
29.3 (0.0 - 182.8) |
30.2 (0.0 - 161.8) |
32.7 (0.1 - 185.5) |
24.0 (0.0 - 161.4)a+ |
25.3 (0.0 - 155.7)a+ |
| Dmean (Gy) |
26.8 (10.9 - 36.4) |
28.0 (11.3 - 40.6) |
28.0 (11.3 - 38.6) |
27.9 (11.0 - 39.4)a |
28.0 (11.0 - 39.5)a+ |
| MU | 701.7 (496–850) | 399.7 (324–515)a+b+ | 457.6 (322–641)a+ | 436.6 (356–590)a+b+ | 460.6 (363–621)a+ |
Single and double arc plans before (1A, 2A) and after modification (1Am, 2Am) of the optimization penalties; values are expressed as the mean (range).
ap < 0.05 for Wilcoxon matched-pair signed rank test vs. IMRT; bp < 0.05 1A vs. 2A; cp < 0.05 1Am vs. 2Am; +p < 0.01.