Figure 1.

Morphology of neurons in rat hippocampal slices following oxygen-glucose deprivation (light microscope, × 200).

Hematoxylin-eosin staining showed lightly stained basophilic granules in the cytoplasm and unclear boundaries between neuronal membranes and surrounding regions in the control (A) and oxygen-glucose deprivation + interleukin-1 receptor antagonist groups (C). Neuronal atrophy, clear boundaries between neuronal cells and surrounding regions, acidophilic granules in the cytoplasm, and vacuole-like changes in some neuronal cells were observed in the oxygen-glucose deprivation group (B).