Table 1. Patient Characteristics.
Factors | Total |
---|---|
Total | 35 |
Year of DLI | |
2004-2006 | 19 |
2007-2009 | 16 |
Age at transplant | |
Median (range), IQR | 51 (1-66), (44-58) |
DLI dose | |
1 × 108 CD 3+/kg | 15 |
0.5 × 108 CD 3+/kg | 20 |
Gender | |
Male | 18 |
Female | 17 |
Donor type | |
Sibling | 30 |
URD | 5 |
Disease | |
AML | 15 (43%) |
MDS/MPD | 7 (20%) |
NHL/Hodgkins | 5 (14%) |
CLL | 3 (8.5%) |
Multiple myeloma | 2 (5.5%) |
ALL, prolymphocytic leukemia | 3 (9%) |
JMML | |
Disease status at | |
CR* | 3 (8.5%) |
Marrow only | 22 (63%) |
EM disease | 7 (20%) |
EM + marrow | 3 (8.5%) |
Months from HCT to relapse (range) | 7 (2.7-105) |
Follow-up among survivors | |
Median (range) in years | 2.3 (0.3-6.2) |
NHL indicates non-Hodgkin lymphoma; CLL, chronic lymphocytic leukemia; ALL, acute lymphocytic leukemia; JMML, juvenile myelomonocytic leukemia; URD, unrelated donor; IQR, interquartile range; EM, extramedullary.
All 3 patients who entered the trial in CR were AML patients who received reinduction chemotherapy before enrollment on this trial.