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. 2013 May 15;8(14):1253–1261. doi: 10.3969/j.issn.1673-5374.2013.14.001

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Copyright: © Neural Regeneration Research

This is an open-access article distributed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike 3.0 Unported, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Neurogenic vasodilatation in response to tracer injection.

(A) Representative laser Doppler perfusion images showing alterations of blood perfusion in the foot immediately after tracer exposure. Like nerve transection injury, exposure of the left tibial nerve to either Fluoro-Gold or True Blue resulted in a prompt cutaneous vasodilatation in the left hind paw, but no apparent vasodilatation was observed after injection with Fluoro-Ruby or saline.

(B) Box chart showing quantification data from laser Doppler perfusion images. Data are expressed as percentiles (n = 10, Kruskal-Wallis test, Dunn's multiple comparison test). ^aP < 0.01, ^bP < 0.001, vs. Fluoro-Ruby group, saline group and sham surgery (sham) group. TN: Tibial nerve.