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. 2014 Jul 11;142(4):594–602. doi: 10.1111/imm.12267

Figure 1.

Figure 1

(a) Principal component analysis (PCA) of the transcriptome expressed on either unstimulated peripheral blood mononuclear cells (PBMCs), PBMCs stimulated in vitro with lipopolysaccharide (LPS) or treated with VGX1027 following LPS administration. The PCA was performed on all genes to determine expression trends within the data set. (b) Hierarchical clustering of PBMCs either stimulated with LPS, LPS+VGX-1027 or unstimulated. Pearson's correlation was used as comparison measurement (c) Non-negative matrix factorization of PBMCs either stimulated with LPS, LPS+VGX-1027 or unstimulated.