Table 2.

Top 30 down-regulated genes by VGX1027 relative to LPS

Gene symbol	P value	Fold change
CCL8	0·000	−48·54
EPR1	0·007	−21·41
CXCL10	0·002	−17·83
DTL	0·003	−13·26
CXCL9	0·001	−11·61
TOP2A	0·006	−10·46
KIAA0101	0·008	−10·26
FAM111B	0·002	−9·80
HMMR	0·006	−9·52
CCNB1	0·009	−8·83
NUF2	0·007	−8·49
TPX2	0·007	−8·28
KIF11	0·006	−7·77
HIST1H2BM	0·006	−7·65
MKI67	0·005	−7·55
TYMS	0·006	−7·31
BANK1	0·001	−7·09
BUB1B	0·005	−6·94
CHEK1	0·006	−6·70
CLC	0·004	−6·68
CEP55	0·007	−6·58
RRM2	0·007	−6·52
CDC6	0·005	−6·33
FCGR3A	0·009	−6·24
PGDS	0·000	−6·18
CPA3	0·000	−6·07
KLRF1	0·004	−5·83
FCGR3A	0·006	−5·78
SH2D1B	0·003	−5·62
C6orf173	0·001	−5·47