Table 3.
Top 30 up-regulated genes by VGX1027 relative to lipopolysaccharide
| Gene symbol | P value | Fold change |
|---|---|---|
| ARMC9 | 0·007 | 3·65 |
| NEFM | 0·008 | 2·34 |
| OR1F2P | 0·004 | 2·17 |
| FBXO2 | 0·006 | 2·12 |
| YPEL2 | 0·001 | 2·09 |
| PI3 | 0·004 | 2·08 |
| KIF5C | 0·007 | 2·03 |
| TUBB4 | 0·005 | 2·03 |
| CACNB3 | 0·006 | 1·99 |
| ETNK2 | 0·001 | 1·98 |
| PTMS | 0·006 | 1·90 |
| BMF | 0·002 | 1·87 |
| LRRC8D | 0·000 | 1·85 |
| FNBP1L | 0·002 | 1·85 |
| CCDC136 | 0·005 | 1·83 |
| STXBP1 | 0·007 | 1·80 |
| DNAJB4 | 0·002 | 1·77 |
| SLC44A1 | 0·008 | 1·75 |
| FLJ40113 | 0·004 | 1·74 |
| RCAN1 | 0·009 | 1·74 |
| TXNRD1 | 0·001 | 1·73 |
| FLJ40125 | 0·008 | 1·72 |
| CDK2AP1 | 0·005 | 1·72 |
| KLF3 | 0·001 | 1·71 |
| SLC38A2 | 0·000 | 1·71 |
| CAMK2N1 | 0·009 | 1·70 |
| SMARCA1 | 0·007 | 1·69 |
| SERPINI1 | 0·004 | 1·67 |
| SLC3A2 | 0·006 | 1·67 |
| GTF2IRD1 | 0·005 | 1·67 |