Figure 6.

Diagram of the Delcath Catheter System. Melphalan is administered directly into the hepatic artery through an infusion catheter placed percutaneously via the femoral artery. Hepatic venous outflow is isolated via a double balloon catheter in the retrohepatic inferior vena cava (IVC) (shown top right). Blood is drawn out of the retrohepatic IVC through multiple fenestrations located along the length of the catheter between the cranial and caudal balloons. The blood is then pumped through a pair of activated charcoal filters prior to return to the systemic circulation via an internal jugular vein catheter. Fluoroscopic image of the isolated, retrohepatic IVC segment obtained by retrograde injection of contrast through the intraballoon fenestrations to confirm the absence of systemic leak is shown in the middle right.