Figure 1.

The features of paediatric malarial retinopathy are: retinal haemorrhages (often white-centred), retinal whitening, and orange or white discolouration of vessels. Papilloedema is often seen but is not specific for cerebral malaria. Angiographic signs include capillary non-perfusion, vessel mottling, and leakage. (A) Colour retinal image showing white-centred haemorrhages and retinal whitening extending from the macula into the temporal periphery (horizontal raphe). (B) Fluorescein angiography shows severe capillary non-perfusion in the retinal periphery (marked in yellow). Capillary non-perfusion typically coincides with retinal whitening. (C) Leakage of fluorescein from retinal venules. (D) Vessel mottling can be seen on a magnified fluorescein angiogram image. Images are from different subjects.