Table 1.
Disorders included in the meta-analysis of grey matter lesions based on previously published voxel-based morphometry (VBM) studies
| Disorder | Number of VBM studies included | Number of patients | Number of healthy controls |
|---|---|---|---|
| Attention deficit hyperactivity disorder | 13 | 363 | 331 |
| Amyotrophic lateral sclerosis | 8 | 132 | 146 |
| Anorexia nervosa | 10 | 156 | 207 |
| Asperger’s syndrome | 9 | 163 | 209 |
| Autism (pervasive developmental disorder excluding Asperger’s syndrome) | 12 | 330 | 331 |
| Bipolar affective disorder | 18 | 479 | 630 |
| Chronic pain | 13 | 305 | 326 |
| Dementia in Alzheimer’s disease | 36 | 765 | 1211 |
| Dementia in Parkinson’s disease | 10 | 192 | 228 |
| Depressive disorder | 24 | 883 | 1015 |
| Developmental dyslexia | 8 | 121 | 122 |
| Dystonia | 10 | 219 | 244 |
| Frontotemporal dementia | 37 | 508 | 660 |
| Hereditary ataxia | 15 | 202 | 223 |
| Huntington’s disease | 9 | 227 | 193 |
| Juvenile myoclonic epilepsy | 7 | 220 | 218 |
| Multiple sclerosis | 11 | 499 | 353 |
| Obsessive-compulsive disorder | 14 | 425 | 431 |
| Obstructive sleep apnoea | 7 | 177 | 268 |
| Panic disorder | 7 | 142 | 133 |
| Parkinson’s disease | 17 | 515 | 411 |
| Progressive supranuclear palsy | 7 | 108 | 182 |
| Post traumatic stress disorder | 14 | 232 | 327 |
| Schizophrenia | 51 | 1925 | 2133 |
| Temporal lobe epilepsy – left | 14 | 339 | 597 |
| Temporal lobe epilepsy – right | 10 | 247 | 373 |
| Total | 392 | 9874 | 11 502 |