Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2014 Jul 21;206(2):217–230. doi: 10.1083/jcb.201401002

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© 2014 Huang et al.

This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 3.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/3.0/).

PMC Copyright notice

Figure 3. — AGO3 inhibits the Aub:Aub Ping-Pong cycle in a Slicer-independent manner. (A) Box plots illustrating the Ping-Pong Z-score values of piRNAs in each phenotype, with whiskers showing the minimum and maximum numbers in the data group. (B) Heatmap of Z-score values for each transposon family in ago3 mutant, uasp-flag-ago3^WT; nosP-gal4:vp16, ago3, and uasp-flag-ago3^DD-AA; nosP-gal4:vp16, ago3 ovaries. (C) The Ping-Pong signal showed the probability of 5′ overlap between sense and antisense piRNAs in Het-A, R1A1, F-element, and opus families in ago3 mutant, uasp-flag-ago3^WT; nosP-gal4:vp16, ago3, and uasp-flag-ago3^DD-AA; nosP-gal4:vp16, ago3 ovaries. (D and E) The nucleotide bias of total TE-derived Ping-Pong piRNAs (D) and Het-A (E) Ping-Pong piRNAs in ago3 mutant, uasp-flag-ago3^WT; nosP-gal4:vp16, ago3, and uasp-flag-ago3^DD-AA; nosP-gal4:vp16, ago3 ovaries. Closed arrowhead, open arrowhead, and asterisks indicate sense 10A, antisense 1U, and antisense 10A, respectively.