Table 1.

Protocol parameters and outcome comparison between RK and SK.

	Protocol parameters
	RK	SK
Number of Days	3	17
Trains per Day	10	1
Inter-Stimulus Interval	20 m	24 h
Stimulus duration (train duration)	10 s	1 s
Train frequency	50 Hz (biphasic)	62.5 Hz (monophasic)
Train pulses width	1.0 ms (square)	1.0 ms (square)
	Protocol outcome
	RK	SK
Total generalized seizures	3.6 ± 0.8 R4	4.8 ± 0.8 R4
	6.4 ± 0.8 R5	7.8 ± 0.8 R5
First AD duration	46.5 ± 5.2 s (R4)	46.4 ± 4.9 s (R4)
	62.3 ± 3.8 s (R5)*	48.7 ± 3.6 s (R5)
Trains needed to reach R4 and R5	9.8 ± 2.8 R4	4.3 ± 0.3 R4
	12.3 ± 1.4 R5*	6.4 ± 0.4 R5
Initial AD thresholds	73.5 ± 13.7 μA*	260 ± 24.5 μA

t-test *p < 0.05.