Table 1.
Type of case | Mean age in years (range) | Gender, number (%) | NCI risk group, number (%) | Mean initial WBC, 103/μl (range) | Mean % blasts in sample (range) | Total cases | SNP array cases | Methylation array cases | Expression array cases |
---|---|---|---|---|---|---|---|---|---|
DS-ALL | 6.5 (2.0–17.0) | 31 female (53.4) 27 male (46.6) | 22 HR (42.3) 30 SR (57.7) | 57.5 (80.3) | 86.1 (9.9) | 58 | 50 | 11 | 23 |
DS paired germline | - | - | - | - | - | 23 | 23 | 0 | 0 |
NDS ALL | 6.5 (1.0–16.0) | 31 female (45.6) 37 male (54.4) | 31 HR (47.7) 34 SR (52.3) | 51.9 (3.0, 765) | 81.4 (46, 100) | 68 | 65 | 7 | 26 |
NDS paired germline | - | - | - | - | - | 12 | 12 | 0 | 0 |
DS indicates Down syndrome; ALL, acute lymphoblastic leukemia; NDS, non-Down syndrome; NCI, National Cancer Institute; WBC, white blood count; SNP, single nucleotide polymorphism; HR, high risk; and SR, standard risk.