Table 3.

Clinical practice and proxy clinical practice outcomes and data collection methods

	Method	Outcome assessment period/timing	Data source	Level data collected	Analysis level
Primary outcome
Appropriate post-traumatic amnesia screening (PTA)	Chart audit (retrospective)	2 month period post-intervention	Hospital record	Patient	Patient
Secondary outcomes
Clinical practice outcomes
PTA screening tool	Chart audit (retrospective)	2 month period post-intervention	Hospital record	Patient	Patient
Memory - clinical assessment	Chart audit (retrospective)	2 month period post-intervention	Hospital record	Patient	Patient
Computed tomography scan - clinical criteria (CT)1	Chart audit (retrospective)	2 month period post-intervention	Hospital record	Patient	Patient
Provision of patient information (INFO)	Chart audit (retrospective)	2 month period post-intervention	Hospital record	Patient	Patient
Safe discharge based on PTA and INFO	Chart audit (retrospective)	2 month period post-intervention	Hospital record	Patient	Patient
Safe discharge based on PTA, CT, and INFO	Chart audit (retrospective)	2 month period post-intervention	Hospital record	Patient	Patient
Proxy measures of clinical practice
Self-report of adherence to recommended practice
• PTA	Staff questionnaire (1-item)	Baseline/Endpoint	Doctors	Staff member	Staff member
			Nurses
• CT	Staff questionnaire (1-item)	Baseline/Endpoint	Doctors	Staff member	Staff member
• INFO	Staff questionnaire (1-item)	Baseline/Endpoint	Doctors	Staff member	Staff member
			Nurses
Behavioural simulation2 to adhere to recommended practice
• PTA	Staff questionnaire (clinical vignettes)	Endpoint	Doctors	Staff member	Staff member
			Nurses
• CT	Staff questionnaire (clinical vignettes)	Endpoint	Doctors	Staff member	Staff member
			Nurses
• INFO	Staff questionnaire (clinical vignettes)	Endpoint	Doctors	Staff member	Staff member
			Nurses

¹Criteria that justify a scan are: age 65 years or older; GCS <15; amnesia; suspected skull fracture; vomiting and coagulopathy (see Additional file 1). ²Clinical decision in response to individual simulated patients, for example in patient scenarios.