Table 2.
Thermogravimetric analysis (TGA) results of SPIONs and calculation of number of surface molecules. Percentages of weight loss of 2-MEA, PEG 2K, and PEG 10K SPIONs stored in DMEM with and without BCS were also measured.
| Nanoparticle coating |
Molecules per nanoparticle |
Surface density (molecules/nm2) |
% Weight loss |
||
|---|---|---|---|---|---|
| pH 9 | DMEM | DMEM+BCS | |||
| Citric Acid | 1430 | 5.22 | 18.7 | N/A | N/A |
| 2-MEA | 839 | 3.06 | 13.1 | 23.1 | 57.2 |
| PEG 550 | 270 | 0.982 | 13.2 | N/A | N/A |
| PEG 2K | 156 | 0.567 | 20.6 | 29.8 | 53.0 |
| PEG 5K | 323 | 1.18 | 56.1 | N/A | N/A |
| PEG 10K | 170 | 0.620 | 56.9 | 24.4 | 56.2 |