Table III.
QTDT analysis. Nominal p-values <0.05 are in bold, italicized numbers and those approaching this significance threshold are shown in italics. AT = Total Test of Association, AW = Within-Test of Association. AP test for stratification effects were not significant for any associated marker at p<0.05. NT = Not tested. X-linked markers tested using UNPHASED, with Chi2 referring to likelihood Chi2 ratios in these instances.
| ADHD Composite | AL Home | AL Lab | |||||||||||||||||
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| Gene | Marker | AT | AW | AT | AW | AT | AW | ||||||||||||
| Chi2 | df | p | Chi2 | df | p | Chi2 | df | p | Chi2 | df | p | Chi2 | df | p | Chi2 | df | p | ||
| DAT1 | rs2550946 | 0.43 | 539.00 | 0.51 | 0.71 | 539.00 | 0.40 | 0.33 | 541.00 | 0.57 | 0.78 | 541.00 | 0.38 | 1.23 | 544.00 | 0.27 | 0.69 | 544.00 | 0.41 |
| 3'UTR VNTR | 7.00 | 610.00 | 0.03 | 5.09 | 610.00 | 0.08 | 2.83 | 612.00 | 0.24 | 1.56 | 612.00 | 0.46 | 1.72 | 615.00 | 0.42 | 0.03 | 615.00 | 0.86 | |
| Int8 VNTR | 3.42 | 606.00 | 0.18 | 2.84 | 606.00 | 0.24 | 2.09 | 608.00 | 0.35 | 0.26 | 608.00 | 0.88 | 0.90 | 611.00 | 0.64 | 0.30 | 611.00 | 0.58 | |
| rs11564750 | 0.06 | 557.00 | 0.80 | 0.75 | 557.00 | 0.39 | 0.03 | 559.00 | 0.87 | 0.21 | 559.00 | 0.65 | 3.98 | 562.00 | 0.05 | 3.38 | 562.00 | 0.07 | |
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| DRD4 | VNTR | 4.74 | 592.00 | 0.19 | 3.26 | 592.00 | 0.35 | 2.85 | 594.00 | 0.42 | 3.38 | 594.00 | 0.34 | 3.62 | 597.00 | 0.31 | 0.77 | 597.00 | 0.38 |
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| NET1 | rs11568324 | 4.38 | 548.00 | 0.04 | NT | NT | NT | 1.44 | 550.00 | 0.23 | NT | NT | NT | 0.04 | 553.00 | 0.85 | NT | NT | NT |
| rs3785157 | 3.68 | 573.00 | 0.06 | 4.65 | 573.00 | 0.03 | 0.16 | 575.00 | 0.69 | 0.00 | 575.00 | 0.97 | 0.24 | 578.00 | 0.63 | 1.03 | 578.00 | 0.31 | |
| rs998424 | 3.30 | 572.00 | 0.07 | 4.42 | 572.00 | 0.04 | 0.09 | 574.00 | 0.76 | 0.00 | 574.00 | 0.95 | 0.31 | 577.00 | 0.58 | 0.66 | 577.00 | 0.42 | |
| rs2242447 | 1.23 | 568.00 | 0.27 | 1.03 | 568.00 | 0.31 | 0.07 | 570.00 | 0.79 | 0.26 | 570.00 | 0.61 | 0.51 | 573.00 | 0.47 | 0.84 | 573.00 | 0.36 | |
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| 5-HTT | rs140701 | 2.96 | 559.00 | 0.09 | 3.03 | 559.00 | 0.08 | 0.40 | 561.00 | 0.53 | 0.17 | 561.00 | 0.68 | 1.37 | 564.00 | 0.24 | 0.99 | 564.00 | 0.32 |
| rs11080121 | 2.16 | 577.00 | 0.14 | 2.71 | 577.00 | 0.10 | 0.25 | 579.00 | 0.62 | 0.31 | 579.00 | 0.58 | 2.35 | 582.00 | 0.13 | 2.23 | 582.00 | 0.14 | |
| rs2020936 | 1.24 | 559.00 | 0.27 | 1.92 | 559.00 | 0.17 | 0.07 | 561.00 | 0.80 | 0.01 | 561.00 | 0.91 | 0.23 | 564.00 | 0.63 | 0.15 | 564.00 | 0.70 | |
| rs2066713 | 0.04 | 561.00 | 0.84 | 0.00 | 561.00 | 1.00 | 0.28 | 563.00 | 0.59 | 0.40 | 563.00 | 0.53 | 0.56 | 566.00 | 0.45 | 0.50 | 566.00 | 0.48 | |
| VNTR | 0.31 | 592.00 | 0.57 | 0.03 | 592.00 | 0.87 | 0.00 | 596.00 | 0.98 | 0.04 | 596.00 | 0.84 | 0.78 | 599.00 | 0.38 | 0.16 | 599.00 | 0.69 | |
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| SNAP25 | rs6039806 | 0.00 | 569.00 | 0.96 | 0.00 | 569.00 | 0.99 | 0.08 | 572.00 | 0.78 | 0.42 | 572.00 | 0.42 | 0.17 | 575.00 | 0.68 | 0.01 | 575.00 | 0.91 |
| rs362987 | 0.04 | 572.00 | 0.84 | 0.07 | 572.00 | 0.79 | 0.01 | 574.00 | 0.93 | 0.18 | 574.00 | 0.18 | 0.35 | 577.00 | 0.55 | 0.26 | 577.00 | 0.61 | |
| rs3746544 | 0.05 | 558.00 | 0.83 | 0.18 | 558.00 | 0.67 | 0.31 | 560.00 | 0.58 | 0.34 | 560.00 | 0.34 | 0.08 | 563.00 | 0.77 | 0.09 | 563.00 | 0.76 | |
| rs1051312 | 0.63 | 555.00 | 0.43 | 0.04 | 555.00 | 0.85 | 0.54 | 557.00 | 0.46 | 0.38 | 557.00 | 0.54 | 1.06 | 560.00 | 0.30 | 0.89 | 560.00 | 0.34 | |
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| MAOA | rs6323 | NT | NT | NT | 1.03 | 1.00 | 0.31 | NT | NT | NT | 0.61 | 1.00 | 0.43 | NT | NT | NT | 0.78 | 1.00 | 0.38 |
| VNTR | NT | NT | NT | 4.68 | 3.00 | 0.20 | NT | NT | NT | 1.14 | 3.00 | 0.77 | NT | NT | NT | 0.72 | 3.00 | 0.87 | |