Table 2.
Fold change (FC) of seventeen elevated and two housekeeping proteins in PsA SF and the corresponding peptides
| Protein description | Gene name | PsA:OA FC | Corresponding SRM peptides |
|---|---|---|---|
| Orosomucoid 1 |
ORM1 |
2.5 |
WFYIASAFR |
| Cathepsin G |
CTSG |
6.7 |
NVNPVALPR |
| Profilin 1 |
PFN1 |
9.0 |
TLVLLMGK |
| Histone 4 |
H4 |
8.6 |
VFLENVIR |
| Histone 2A type I A |
H2AFX |
9.7 |
NDEELNK |
| Brain acid soluble protein 1 |
BASP1 |
7.4 |
ESEPQAAAEPAEAK |
| 22 kDa interstitial collagenase |
MMP1 |
6.1 |
DIYSSFGFPR |
| Leukocyte elastase inhibitor |
SERPINB1 |
4.3 |
LGVQDLFNSSK |
| Myeloperoxidase |
MPO |
3.9 |
IGLDLPALNMQR |
| Plastin 2 |
PLS2 |
3.9 |
NWMNSLGVNPR |
| Galectin-3-binding protein |
M2BP |
3.8 |
AVDTWSWGER |
| C4b-binding protein |
C4BP |
2.1 |
YTCLPGYVR |
| C-reactive protein |
CRP |
18.7 |
ESDTSYVSLK |
| Protein S100A9 |
S100A9 |
18.9 |
LTWASHEK |
| Stromelysin 1 |
MMP3 |
10.6 |
VWEEVTPLTFSR |
| Neutrophil alpha defensin 1 |
DEFA1 |
13.1 |
IPACIAGER |
| CD5-like protein |
CD5L |
3.0 |
IWLDNVR |
| Leucine-rich alpha-2-glycoprotein 1* |
LRG1 |
1.0 |
DLLLPQPDLR |
| GQTLLAVAK | |||
| Complement Factor I* |
CFI |
1.0 |
FSVSLK |
| YTHLSCDK |
*Denotes the housekeeping proteins, and the corresponding peptides.