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. 2014 Jul 17;10:425–434. doi: 10.2147/VHRM.S63298

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© 2014 Camm et al. This work is published by Dove Medical Press Limited, and licensed under Creative Commons Attribution – Non Commercial (unported, v3.0) License

The full terms of the License are available at http://creativecommons.org/licenses/by-nc/3.0/. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed.

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XANTUS study design, an observational, single-arm cohort study. The objective is to collect real-life data on adverse events, bleeding, thromboembolic events, and mortality in patients with nonvalvular AF treated with rivaroxaban. The same basic design will be used for all studies in the XANTUS program.

Notes: ^aProtocol does not define exact referral dates for follow-up visits (every 3 months recommended); ^bin patients discontinuing rivaroxaban before 1 year, the end of the observation period is 30 days after the last dose. XANTUS (ClinicalTrials.gov: NCT01606995).

Abbreviations: AF, atrial fibrillation; CNS, central nervous system; XANTUS, Xarelto^® for Prevention of Stroke in Patients with Atrial Fibrillation.