Figure 4.
Individual chromosomes in CXB and BXH mice associated with TSAb activity or TSH binding inhibition (TBI) after two A-subunit-Ad immunizations in the present and previous studies 14,17: A) Chr 12: Mouse-TSHR TSAb for CXB mice and human-TSHR TSAb for BXH mice; B) Chr 12: Ratios for mouse:human TSHR TSAb for BXH mice and human:mouse TSAb for CXB mice; C) Chr 17: TBI (inhibition of TSH binding) for CXB mice and human-TSHR TSAb; D) Chr X: TBI (inhibition of TSH binding) for CXB mice and human-TSHR TSAb. Chromosomal distances (megabases) are on the horizontal axes and Likelihood Ratio Statistics are on the vertical axes. GeneNetwork identifiers: A) CXB GN 10685 and BXH GN 10147; B) BXH GN10157 and CXB GN 10686; C) GN 10512 and GN 10683; D)GN 10512 and GN 10683.