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The gut microbiome as a therapeutic target: the “drug the extended” genome strategy. Perturbed metagenomic or metabonomic profiles associated with complex disease states can be restored to homeostasis with rationally selected antibiotic, probiotic, prebiotic, or combination treatment strategies. Adapted with permission from Macmillan Publishers Ltd: Nature Reviews Drug Discovery,23 copyright 2008. http://www.nature.com/nrd/.
