Table 2. ABR thresholds.
| Average ABR threshold (dB SPL) | Controls vs injected | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| No. of mice tested | 8 kHz | SEM | 16 kHz | SEM | 24 kHz | SEM | 32 kHz | SEM | P values | |
| 5 | Controls | 38.6 | 0.9 | 27.2 | 2.5 | 28.7 | 2.9 | 43.0 | 2.2 | N/A |
| 10 | AAV2/1 | 35.7 | 1.3 | 26.2 | 2.0 | 27.4 | 2.6 | 46.5 | 2.6 | 1.000 |
| 9 | AAV2/2 | 37.9 | 3.5 | 28.2 | 1.5 | 24.3 | 2.2 | 43.5 | 6.2 | 0.995 |
| 11 | AAV2/8 | 37.8 | 1.6 | 25.7 | 3.5 | 28.8 | 1.7 | 47.5 | 1.9 | 0.999 |
| 11 | Lentivirus | 49.7 | 2.9 | 35.1 | 4.4 | 37.7 | 2.8 | 58.5 | 2.7 | <0.001 |
Auditory brain-stem response (ABR) thresholds in decibels sound pressure level (dB SPL) with associated standard errors of the mean for each of four pure tone frequencies are shown. Only the lentivirus group shows a statistically significant difference (P < 0.001) from control ABR thresholds.