Table 3. Top Genes showing decreased methylation (<−2.0 fold) in HIV-seropositive METH users in comparison to the HIV-seropositive non-user group.

REF ACC #	Gene Name	Probeset ID	Fold change	P value	CHR
NM_052909	PLEKHG4B	cg18816122	−14.14	0.00319	5
NM_001052	SSTR4	cg01471923	−8.33	0.00206	20
NM_207189	BRDT	cg01081438	−6.47	0.00352	1
NM_138286	ZNF681	cg25958450	−4.93	0.00397	19
NM_005633	SOS1	cg02502145	−4.76	0.00038	2
NM_001163	APBA1	cg14460215	−4.21	0.00229	9
NM_024027	COLEC11	cg10724632	−4.07	0.00015	2
NM_002217	ITIH3	cg05393861	−3.90	0.00085	3
NM_021729	VPS11	cg01385018	−3.29	0.00162	11
NM_020728	ESYT2	cg13211008	−3.22	0.00102	7
NM_001165963	SCN1A	cg00881894	−3.13	0.00048	2
NM_001101426	ISPD	cg11973981	−2.91	0.00333	7
NM_001009991	SYTL3	cg06426293	−2.91	0.00545	6
NM_001145670	SORBS2	cg09120722	−2.87	0.00307	4
NM_000705	ATP4B	cg06955954	−2.63	0.00025	13
NM_206918	DEGS2	cg20904336	−2.52	0.00159	14
NM_005461	MAFB	cg12499119	−2.37	0.00018	20
NM_001098796	TOX2	cg26365090	−2.31	0.00065	20
NR_001298	HLA-DRB6	cg25140213	−2.19	0.00170	6
NM_020133	AGPAT4	cg09655876	−2.16	0.00152	6
NM_001164759	PRKAR1B	cg10117599	−2.16	0.00002	7
NM_080425	GNAS	cg23484981	−2.16	0.00035	20
NM_024686	TTLL7	cg10977910	−2.15	0.00085	1
NR_029411	LOC100133091	cg17404449	−2.15	0.00046	7
NM_001039841	ARHGAP11B	cg18739374	−2.05	0.00113	15
NM_001143974	ASAH2	cg22645355	−2.01	0.00085	10