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. 2014 Jul 23;9(7):e102119. doi: 10.1371/journal.pone.0102119

Table 2. Summary Table.

Data Set Data Types Analyzed HIHI HILO LOLO LOHI
GBM {Copy Number Alteration, Expression} 202385 178195 52592 15777
{DNA methylation, Expression} 2875172 1008334 2671091 266135
{Mutation, Broad CNAs} 170 54 0 0
{Mutation, DNA methylation} 1057 238 8 0
OV {Copy Number Alteration, Expression} 271472 823660 8544 1471
{DNA methylation, Expression} 70498 116200 93543 35934
{Mutation, Broad CNAs} 75 5 0 0
{Mutation, DNA methylation} 319 670 33 60

Number of different Boolean implications between variables of different data types in the TCGA GBM and OV data sets. The different data types considered were mutation, copy number, DNA methylation and gene expression. Since chromosomes tended to be altered in large blocks, the copy number data were also organized by chromosomal segments. GISTIC2.0 [36] identifies focal peaks of amplification or deletion as well as broad regions of alteration. The segments derived by GISTIC2.0 are referred to as broad CNAs.