Table 2. Summary Table.
Data Set | Data Types Analyzed | HIHI | HILO | LOLO | LOHI |
GBM | {Copy Number Alteration, Expression} | 202385 | 178195 | 52592 | 15777 |
{DNA methylation, Expression} | 2875172 | 1008334 | 2671091 | 266135 | |
{Mutation, Broad CNAs} | 170 | 54 | 0 | 0 | |
{Mutation, DNA methylation} | 1057 | 238 | 8 | 0 | |
OV | {Copy Number Alteration, Expression} | 271472 | 823660 | 8544 | 1471 |
{DNA methylation, Expression} | 70498 | 116200 | 93543 | 35934 | |
{Mutation, Broad CNAs} | 75 | 5 | 0 | 0 | |
{Mutation, DNA methylation} | 319 | 670 | 33 | 60 |
Number of different Boolean implications between variables of different data types in the TCGA GBM and OV data sets. The different data types considered were mutation, copy number, DNA methylation and gene expression. Since chromosomes tended to be altered in large blocks, the copy number data were also organized by chromosomal segments. GISTIC2.0 [36] identifies focal peaks of amplification or deletion as well as broad regions of alteration. The segments derived by GISTIC2.0 are referred to as broad CNAs.