Table 2.
Region | Cluster | BA | Lat. | x | y | z | AnLE | Volume (mm3) |
---|---|---|---|---|---|---|---|---|
FDG-PET | ||||||||
L. subcallosal area, posterior gyrus rectus, caudate head, nucleus accumbens |
F1 | 11-14/25 | L. | −8 −8 |
10 20 |
−14 −24 |
0.0186 0.0164 |
2631 |
L. caudate head & body, nucleus lentiformis |
F2 | L. | −10 −18 |
10 8 |
2 4 |
0.0155 0.0139 |
1480 | |
Bl. middle gyrus rectus | F3 | 11/13/14 | Bl. | −2 | 42 | −24 | 0.0165 | 1192 |
Bl. middle thalamus | F4 | Bl. | 2 10 |
−18 −20 |
4 6 |
0.0152 0.0123 |
1096 | |
L. superior anterior insula | F5 | 15 | L. | −42 | 12 | 0 | 0.0152 | 816 |
L. posterior inferior frontal sulcus/inferior frontal junction |
F6 | 6/9/44 | L. | −46 | 18 | 32 | 0.0127 | 568 |
| ||||||||
MRI | ||||||||
Bl. subcallosal area, caudate head & body, nucleus accumbens |
M1 | 25 | Bl. | 2 8 −8 |
8 12 14 |
−6 10 6 |
0.0292 0.0289 0.0257 |
4832 |
Bl. pregenual anterior cingulate, anterior midcingulate and paracingulate gyrus, anterior frontomedian cortex |
M2 | 9/32/33 | Bl. | −2 0 0 |
36 46 36 |
14 26 38 |
0.0291 0.0271 0.0156 |
4744 |
Bl. anterior frontomedian cortex | M3 | 10/12 | Bl. | 0 | 54 | −4 | 0.0348 | 1552 |
L. anterior inferior insula | M4 | 16 | L. | −40 −44 |
18 8 |
−12 −8 |
0.0279 0.0107 |
1488 |
R. anterior superior insula, putamen |
M5 | 15 | R. | 28 36 |
6 18 |
8 6 |
0.0194 0.0166 |
1264 |
Clusters above an anatomical likelihood estimate (AnLE) threshold p<0.05, false discovery rate (FDR) corrected for multiple comparisons, are listed. Coordinates are in MNI space. BA Brodmann area, Bl. Bilateral, bvFTD behavioral variant frontotemporal dementia, FDG-PET 18F-fluorodeoxyglucose positron emission tomography, L. left, Lat. Lateralization, MNI Montreal Neurological Institute, MRI magnetic resonance imaging, R. right.