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. Author manuscript; available in PMC: 2015 Aug 1.
Published in final edited form as: Cortex. 2014 Mar 21;0:22–37. doi: 10.1016/j.cortex.2014.02.022

Table 2.

Results of the meta-analysis identifying bvFTD’s neural correlates with anatomical likelihood estimates

Region Cluster BA Lat. x y z AnLE Volume
(mm3)
FDG-PET
L. subcallosal area, posterior
gyrus rectus, caudate head,
nucleus accumbens
F1 11-14/25 L. −8
−8
10
20
−14
−24
0.0186
0.0164
2631
L. caudate head & body,
nucleus lentiformis
F2 L. −10
−18
10
8
2
4
0.0155
0.0139
1480
Bl. middle gyrus rectus F3 11/13/14 Bl. −2 42 −24 0.0165 1192
Bl. middle thalamus F4 Bl. 2
10
−18
−20
4
6
0.0152
0.0123
1096
L. superior anterior insula F5 15 L. −42 12 0 0.0152 816
L. posterior inferior frontal
sulcus/inferior frontal junction
F6 6/9/44 L. −46 18 32 0.0127 568

MRI
Bl. subcallosal area, caudate
head & body, nucleus
accumbens
M1 25 Bl. 2
8
−8
8
12
14
−6
10
6
0.0292
0.0289
0.0257
4832
Bl. pregenual anterior
cingulate, anterior midcingulate
and paracingulate gyrus,
anterior frontomedian cortex
M2 9/32/33 Bl. −2
0
0
36
46
36
14
26
38
0.0291
0.0271
0.0156
4744
Bl. anterior frontomedian cortex M3 10/12 Bl. 0 54 −4 0.0348 1552
L. anterior inferior insula M4 16 L. −40
−44
18
8
−12
−8
0.0279
0.0107
1488
R. anterior superior insula,
putamen
M5 15 R. 28
36
6
18
8
6
0.0194
0.0166
1264

Clusters above an anatomical likelihood estimate (AnLE) threshold p<0.05, false discovery rate (FDR) corrected for multiple comparisons, are listed. Coordinates are in MNI space. BA Brodmann area, Bl. Bilateral, bvFTD behavioral variant frontotemporal dementia, FDG-PET 18F-fluorodeoxyglucose positron emission tomography, L. left, Lat. Lateralization, MNI Montreal Neurological Institute, MRI magnetic resonance imaging, R. right.