Skip to main content
. Author manuscript; available in PMC: 2015 Aug 1.
Published in final edited form as: J Immunol. 2014 Jun 30;193(3):1301–1313. doi: 10.4049/jimmunol.1303479

FIGURE 3.

FIGURE 3

Elevated miR-190b expression in the colon (A) and jejunum (B) during SIV infection compared to uninfected normal controls and non-SIV-infected macaques with diarrhea (indicated as Colitis). Note the absence of miR-190b upregulation in non-SIV-infected macaques with diarrhea and colitis suggesting that upregulation of miR-190b is not inflammation driven but occurs in response to viral replication (DPI- days post infection). Arrows in colon (A) and jejunum (B) point to two animals [T108 (7DPI) and CG32 (21-29DPI)] that had no detectable SIV in intestinal tissue and where the levels of miR-190b was no different from controls. Data analysis using non-parametric Kruskal-Wallis test revealed differences among groups in both colon (p=0.0002) and jejunum (p<0.0001). Asterisks (* = p<0.05, ** = p<0.01) indicate groups that showed statistical significance compared to uninfected controls following Dunn's multiple groups comparison test. The error bars represent standard error of mean fold change within each group.