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. Author manuscript; available in PMC: 2015 Aug 1.
Published in final edited form as: Heart Rhythm. 2014 Apr 24;11(8):1411–1417. doi: 10.1016/j.hrthm.2014.04.032

Table 3.

Demographic group statistics for vagus nerve group variable averages

Group Variable Average Mean Median Min Max First
Quartile
Third
Quartile
Uncorr.
p-
value*
Sex Male (n = 20) Bundles (number) 8.72 6.88 1 20.25 5.38 11.25 Bundles 0.895 C.S.A 0.730 TH.F. 0.792
Cross sectional area (mm2) 1.36 1.33 0.77 2.66 1.09 1.60
TH positive area fraction (%) 5.38 4.33 0.01 22.35 0.71 7.64
Female (n = 11) Bundles (number) 9.02 7.5 2 20.25 5.88 10.5
Cross sectional area (mm2) 1.87 1.28 0.55 6.77 1.12 1.93
TH positive area fraction (%) 4.13 3.57 0.01 10.62 1.49 5.92

Ethnicity Caucasian (n = 20) Bundles (number) 9.91 8.62 2 20.25 5.94 11.25 Bundles 0.122 C.S.A 0.679 TH.F. 0.331
Cross sectional area (mm2) 1.68 1.27 0.55 6.77 1.09 1.85
TH positive area fraction (%) 4.96 4.7 0.01 15.08 1.62 7.58
Hispanic (n = 4) Bundles (number) 4.69 4.38 3 7 3.56 5.5
Cross sectional area (mm2) 1.09 1.06 0.78 1.46 0.93 1.21
TH positive area fraction (%) 10.05 7.88 2.10 22.35 6.07 11.87
Asian (n = 1) Bundles (number) 4.5 4.5 4.5 4.5 4.5 4.5
Cross sectional area (mm2) 1.27 1.27 1.27 1.27 1.27 1.27
TH positive area fraction (%) 0.79 0.79 0.79 0.79 0.79 0.79
Native American (n = 1) Bundles (number) 6 6 6 6 6 6
Cross sectional area (mm2) 1.30 1.30 1.30 1.30 1.30 1.30
TH positive area fraction (%) 0.87 0.87 0.87 0.87 0.87 0.87

Cardiovascular disease Present (n = 20) Bundles (number) 7.94 6.75 1 20.25 5.56 9.81 Bundles 0.375 C.S.A 0.919 TH.F. 0.317
Cross sectional area (mm2) 1.63 1.29 0.77 6.77 1.05 1.69
TH positive area fraction (%) 5.83 4.70 0.01 22.35 1.79 8.49
Not Present (n = 11) Bundles (number) 10.45 7.5 3.5 20.25 5.62 15.12
Cross sectional area (mm2) 1.39 1.27 0.55 2.66 1.09 1.54
TH positive area fraction (%) 3.31 2.01 0.22 9.50 0.62 5.68

Neurodegenerative disease Present (n = 12) Bundles (number) 10.1 7.25 2 19.5 6.75 13.19 Bundles 0.282 C.S.A 0.059 TH.F. 0.389
Cross sectional area (mm2) 1.16 1.16 0.55 1.98 0.86 1.41
TH positive area fraction (%) 5.34 4.80 0.22 15.08 2.93 6.76
Not Present (n = 19) Bundles (number) 8.03 6 1 20.25 4.75 10.5
Cross sectional area (mm2) 1.78 1.38 0.78 6.77 1.19 1.86
TH positive area fraction (%) 4.68 2.33 0.01 22.35 0.40 7.88

CHF and/or depression Present (n = 10) Bundles (number) 7.78 6.38 2 20.25 4.19 9.81 Bundles 0.434 C.S.A 0.287 TH.F. 0.348
Cross sectional area (mm2) 1.28 1.18 0.81 2.49 1.01 1.39
TH positive area fraction (%) 5.56 3.92 0.87 15.08 2.16 8.49
Not Present (n = 21) Bundles (number) 9.33 7 1 20.25 5.75 11.25
Cross sectional area (mm2) 1.67 1.38 0.55 6.77 1.13 1.83
TH positive area fraction (%) 4.64 4.38 0.01 22.35 0.34 6.63

TH: anti-Tyrosine Hydroxylase antibody, CHF: Chronic heart failure, C.S.A: cross sectional area, TH.F.: anti-Tyrosine Hydroxylase antibody positive area fraction

*

The uncorrected p-values given were not statistically significant before or after adjustment for multiple testing using a Bonferroni correction factor of 21.

Excluding five cases with unknown ethnicity.