Table 3.
Demographic group statistics for vagus nerve group variable averages
| Group | Variable Average | Mean | Median | Min | Max | First Quartile |
Third Quartile |
Uncorr. p- value* |
|
|---|---|---|---|---|---|---|---|---|---|
| Sex | Male (n = 20) | Bundles (number) | 8.72 | 6.88 | 1 | 20.25 | 5.38 | 11.25 | Bundles 0.895 C.S.A 0.730 TH.F. 0.792 |
| Cross sectional area (mm2) | 1.36 | 1.33 | 0.77 | 2.66 | 1.09 | 1.60 | |||
| TH positive area fraction (%) | 5.38 | 4.33 | 0.01 | 22.35 | 0.71 | 7.64 | |||
| Female (n = 11) | Bundles (number) | 9.02 | 7.5 | 2 | 20.25 | 5.88 | 10.5 | ||
| Cross sectional area (mm2) | 1.87 | 1.28 | 0.55 | 6.77 | 1.12 | 1.93 | |||
| TH positive area fraction (%) | 4.13 | 3.57 | 0.01 | 10.62 | 1.49 | 5.92 | |||
| Ethnicity† | Caucasian (n = 20) | Bundles (number) | 9.91 | 8.62 | 2 | 20.25 | 5.94 | 11.25 | Bundles 0.122 C.S.A 0.679 TH.F. 0.331 |
| Cross sectional area (mm2) | 1.68 | 1.27 | 0.55 | 6.77 | 1.09 | 1.85 | |||
| TH positive area fraction (%) | 4.96 | 4.7 | 0.01 | 15.08 | 1.62 | 7.58 | |||
| Hispanic (n = 4) | Bundles (number) | 4.69 | 4.38 | 3 | 7 | 3.56 | 5.5 | ||
| Cross sectional area (mm2) | 1.09 | 1.06 | 0.78 | 1.46 | 0.93 | 1.21 | |||
| TH positive area fraction (%) | 10.05 | 7.88 | 2.10 | 22.35 | 6.07 | 11.87 | |||
| Asian (n = 1) | Bundles (number) | 4.5 | 4.5 | 4.5 | 4.5 | 4.5 | 4.5 | ||
| Cross sectional area (mm2) | 1.27 | 1.27 | 1.27 | 1.27 | 1.27 | 1.27 | |||
| TH positive area fraction (%) | 0.79 | 0.79 | 0.79 | 0.79 | 0.79 | 0.79 | |||
| Native American (n = 1) | Bundles (number) | 6 | 6 | 6 | 6 | 6 | 6 | ||
| Cross sectional area (mm2) | 1.30 | 1.30 | 1.30 | 1.30 | 1.30 | 1.30 | |||
| TH positive area fraction (%) | 0.87 | 0.87 | 0.87 | 0.87 | 0.87 | 0.87 | |||
| Cardiovascular disease | Present (n = 20) | Bundles (number) | 7.94 | 6.75 | 1 | 20.25 | 5.56 | 9.81 | Bundles 0.375 C.S.A 0.919 TH.F. 0.317 |
| Cross sectional area (mm2) | 1.63 | 1.29 | 0.77 | 6.77 | 1.05 | 1.69 | |||
| TH positive area fraction (%) | 5.83 | 4.70 | 0.01 | 22.35 | 1.79 | 8.49 | |||
| Not Present (n = 11) | Bundles (number) | 10.45 | 7.5 | 3.5 | 20.25 | 5.62 | 15.12 | ||
| Cross sectional area (mm2) | 1.39 | 1.27 | 0.55 | 2.66 | 1.09 | 1.54 | |||
| TH positive area fraction (%) | 3.31 | 2.01 | 0.22 | 9.50 | 0.62 | 5.68 | |||
| Neurodegenerative disease | Present (n = 12) | Bundles (number) | 10.1 | 7.25 | 2 | 19.5 | 6.75 | 13.19 | Bundles 0.282 C.S.A 0.059 TH.F. 0.389 |
| Cross sectional area (mm2) | 1.16 | 1.16 | 0.55 | 1.98 | 0.86 | 1.41 | |||
| TH positive area fraction (%) | 5.34 | 4.80 | 0.22 | 15.08 | 2.93 | 6.76 | |||
| Not Present (n = 19) | Bundles (number) | 8.03 | 6 | 1 | 20.25 | 4.75 | 10.5 | ||
| Cross sectional area (mm2) | 1.78 | 1.38 | 0.78 | 6.77 | 1.19 | 1.86 | |||
| TH positive area fraction (%) | 4.68 | 2.33 | 0.01 | 22.35 | 0.40 | 7.88 | |||
| CHF and/or depression | Present (n = 10) | Bundles (number) | 7.78 | 6.38 | 2 | 20.25 | 4.19 | 9.81 | Bundles 0.434 C.S.A 0.287 TH.F. 0.348 |
| Cross sectional area (mm2) | 1.28 | 1.18 | 0.81 | 2.49 | 1.01 | 1.39 | |||
| TH positive area fraction (%) | 5.56 | 3.92 | 0.87 | 15.08 | 2.16 | 8.49 | |||
| Not Present (n = 21) | Bundles (number) | 9.33 | 7 | 1 | 20.25 | 5.75 | 11.25 | ||
| Cross sectional area (mm2) | 1.67 | 1.38 | 0.55 | 6.77 | 1.13 | 1.83 | |||
| TH positive area fraction (%) | 4.64 | 4.38 | 0.01 | 22.35 | 0.34 | 6.63 | |||
TH: anti-Tyrosine Hydroxylase antibody, CHF: Chronic heart failure, C.S.A: cross sectional area, TH.F.: anti-Tyrosine Hydroxylase antibody positive area fraction
*
The uncorrected p-values given were not statistically significant before or after adjustment for multiple testing using a Bonferroni correction factor of 21.
†
Excluding five cases with unknown ethnicity.