Table 4.
Odds ratios (OR) for association of symptom cluster and single symptom with five-year mortality from unadjusted and covariate-adjusted logistic regression modelling
| Five-year mortality |
||
|---|---|---|
| Unadjusted OR (95% CI) | †Adjusted OR (95% CI) | |
| Symptom cluster | ||
| Subgroup 1 | 1 | 1 |
| Subgroup 2 | 1·51* (1·01–2·27) | 1·27 (0.82–1·99) |
| Subgroup 3 | 1·92* (1·29–2·86) | 1·75* (1·12–2·74) |
| Dyspnoea‡ | ||
| ≤51 | 1 | |
| 52–65 | 1·35 (0.90–2·03) | |
| ≥66 | 1·87* (1·26–2·79) | |
| Anxiety‡ | ||
| ≤26 | 1 | |
| 27–36 | 1·08 (0.71–1·63) | |
| ≥37 | 1·33 (0.88–2·01) | |
| Depression‡ | ||
| ≤5 | 1 | |
| 6–9 | 1·40 (0.91–2·13) | |
| ≥10 | 1·90* (1·28–2·84) | |
| Fatigue‡ | ||
| ≥51 | 1 | |
| 31–50 | 1·01 (0.69–1·48) | |
| ≤30 | 1·29 (0.86–1·95) | |
p<0.05.
Covariates include age, gender, race, education level, income level, marital status, pack years of smoking, FEV1% predicted, PaCO2, physical component scale in MOS-36 and number of healthcare use.
Scores were from University of California, San Diego, Shortness of Breath Questionnaire, Spielberger State-Trait Anxiety Inventory, Beck Depression Inventory and vitality subscale in Medical Outcomes Study 36-Item Short-Form Health Survey.
For this analysis, we used cutpoints that divided the sample into three equal groups for each of the single symptoms.
All analyses were performed separately.