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. Author manuscript; available in PMC: 2014 Oct 1.
Published in final edited form as: Genet Epidemiol. 2014 May 6;38(5):416–429. doi: 10.1002/gepi.21810

Figure 1.

Figure 1

Non-linear GEI model: the (red) sigmoid curve shows the true relationship between Y -G association and E, namely, βG(E) = 2 exp(E − 50)/{1 + exp(E − 50)} +2; the boxplots show the covariate heterogeneity of E across studies where the dots show the corresponding covariate means of E.