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The effect of multi-state mechanism on the noise in gene expression. (a) Schematic of multi-inactive-active-state model of gene expression. (b)–(d) The noise strength as a function of the parameter k ≡ λ4 = λ′4 = λ5 = λ′5 = λ6 = λ′6. The other parameter values used in computation are λ1 = 2, λ2 = 1, λ3 = 1, γ2 = 1, γ3 = 1, μ = 5 and (b) γ1 = 1, (c) γ1 = 2, (d) γ1 = 1.7.
