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. Author manuscript; available in PMC: 2015 Jul 1.
Published in final edited form as: Osteoarthritis Cartilage. 2014 May 21;22(7):912–917. doi: 10.1016/j.joca.2014.05.013

Table 4.

Least square means (Tukey-adjusted 95% CI) bone-on-bone forces and knee external moments during walking for BMI and alignment, controlling for gender and walking speed. The interaction between BMI and alignment was not statistically significant hence; the main effects of BMI and alignment are reported. Mean body weight = 912 N (93 kg).

Knee Joint
Load
BMI (kg·m−2) Alignment

27 – 29.9

Overweight
30 – 34.9

Class 1
Obese
35 – 41.3

Class 2+
Obese
P-value

BMI
category
<0°

Valgus
0°–2°

Neutral
>2°

Varus
P-value
Alignment
Compressive Force (N) 2411 (2182, 2639) 2772 (2602, 2943) 2993 (2796, 3190) 0.0006 2734 (2520, 2949) 2651 (2430, 2871) 2791 (2634, 2948) 0.58
Shear Force (N) 369 (322, 415) 418 (384, 453) 472 (432, 513) 0.004 394 (351, 438) 435 (390, 480) 429 (397, 461) 0.33
PF Force (N) 402 (292, 511) 459 (378, 540) 492 (398, 586) 0.45 452 (348, 555) 410 (305, 515) 491 (416, 565) 0.44
Knee Adduction Moment (Nm) 26.4 (22.6, 30.3) 30.4 (27.5, 33.3) 26.6 (23.3, 29.9) 0.12 18.7 (15.1, 22.4) 27.7 (24.0, 31.4) 37.0 (34.4, 39.7) <0.0001
Knee Flexion Moment (Nm) 33.5 (26.6, 40.4) 36.7 (31.6, 41.9) 41.7 (35.8, 47.7) 0.17 35.6 (29.2, 42.1) 37.1 (30.4, 43.7) 39.2 (34.5, 43.9) 0.65

Pairwise significant differences:

Compressive force: Overweight vs Class 1, Overweight vs. Class 2+

Shear force: Overweight vs. Class 2+, Class 1 vs. Class 2+

Knee Adduction: All alignment categories were significantly different at a Tukey adjusted 0.05 level.