Table 2. Adverse gastrointestinal events following administration of a single dose of ACNU.

ACNU Dose (mg/m2)	# of dogs	Grade of anorexia*					Grade of vomiting*					Grade of diarrhea*
		0	1	2	3	4	0	1	2	3	4	0	1	2	3	4
25 (1st cohort)	3	1	2	0	0	0	1	2	0	0	0	2	1	0	0	0
25 (2nd cohort)	3	2	1	0	0	0	2	0	1	0	0	3	0	0	0	0
30	2	2	0	0	0	0	2	0	0	0	0	2	0	0	0	0

*See Apendix Table A1 for grading criteria.