Table 1.
Damage scoring of infected murine lungs
| Days & mice | % lung affected | Alveolar septae | Hemorrhage | Fibrin | Infiltrate | Score |
|---|---|---|---|---|---|---|
| 7 dpi | ||||||
| Infected 1 | 30 | 3 | 1 | 1 | 3 | 3.9 |
| Infected 2 | 40 | 3 | 1 | 1 | 3 | 5.2 |
| Infected 3 | 30 | 3 | 1 | 1 | 3 | 3.9 |
| Infected 4 | 50 | 3 | 1 | 1 | 3 | 6.5 |
| 15 dpi | % lung affected | |||||
| Infected 1 | 60 | |||||
| Infected 2 | 70 | |||||
| Infected 3 | 60 | |||||
| Infected 4 | 40 |
Note: Histopathologic scoring to determine the homogeneity of lung damage at 7 and 15 dpi. The formula to derive the scores at 7 dpi is:% infected × [alveolar hemorrhage + 2(alveolar inflitrates) + 3(fibrin) + alveolar septal congestion].