Table 1.
Clinical and demographic characteristics of subjects with MDD and healthy volunteers (means ± SD are presented).
| Characteristic | Healthy volunteers (n = 10) | Major depressive disorder (n = 11) | p-Value |
|---|---|---|---|
| Age in years | 25.7 ± 2.6 | 34.6 ± 9.5 | 0.012 |
| Female (%) | 5/10 (50) | 6/11 (54) | 0.835 |
| Caucasian (%) | 6/10 (60) | 5/11 (45) | 0.504 |
| Hispanic (%) | 2/10 (20) | 2/11 (18) | 0.916 |
| Smoker (%) | 1/10 (10) | 3/11 (27) | 0.304 |
| Married (%) | 1/10 (10) | 1/11 (9) | n/a |
| Body mass index (kg/m2) | 23.6 ± 2.8 | 23.7 ± 4.3* | 0.95 |
| Illness duration in years | n/a | 9.2 ± 6.2 | n/a |
| Years of education | 15.3 ± 3.5 | 17.2 ± 4.1 | 0.270 |
| QIDS-SR16 | 3.3 ± 4.7 | 16.8 ± 4.7 | <0.001 |
| Anhedonia score | 1.5 ± 1.2 | 5.6 ± 1.4 | <0.001 |
QIDS-SR16 – Quick Inventory of Depressive Symptomatology Self Report 16 Item; Anhedonia Score = QIDS-SR item #13 + MFI item #4.
*
n = 10.