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Anti-fibrotic effect of EPO or CEPO in remnant kidney. To elucidate the intracellular signaling implicated in interstitial fibrosis, we examined the expression of TGF-β1 and collagen I mRNA (a). We also examined Smad3 and phosphorylated Smad3 protein (b). (*p < 0.05; **p < 0.01)
