Figure 7. KS370G reduces the expression of PAI-1 in NRK52E and HK-2 cells induced by TGF-β₁.

(A and C) PAI-1 expression were determined by western blotting of NRK52E and HK-2 cells cultured with different concentration of KS370G (0.1 to 3 μM) for 72 h under TGF-β₁ stimulation. (B and D) Quantitative results presented as mean ± SEM of the signal's optical density in NRK52E cells (B; n = 5) and in HK-2 cells (D; n = 3). *P < 0.05 compared with control group. #P < 0.05 compared with TGF-β₁ (5 ng/ml) groups.