Table 1. Lysine 898 is an evolutionarily conserved residue in BRCA1.
Species | Accession Number | Starting Residue No. | Sequence | Ending Residue No. |
---|---|---|---|---|
Human | P38398 | 893 | KKQSPKVTFECEQKEE | 908 |
Gorilla | Q6J6I8 | 893 | KKQSPKVTFECEQKEE | 908 |
Orangutan | Q6J6J0 | 893 | KKQSPKVTFECEQKEE | 908 |
Chimpanzee | Q9GKK8 | 893 | KKQSPKVTFEREQKEQ | 908 |
Macaque | Q6J6I9 | 892 | KKQSPKVTSECEQKEE | 907 |
Mouse | P48754 | 879 | KELSPKVTAKGKQKER | 894 |
Rat | O54952 | 883 | REPSPKVTSRGEQKER | 898 |
Pig | A5A751 | 884 | REQSPKVTHEGGQKDE | 899 |
Horse | F6SQ43 | 894 | RKRSPKVTLKCGQKEG | 909 |
Dog | Q95153 | 891 | GKQGPKVTLECGQKEE | 906 |
UniProtKB accession numbers for each BRCA1 homolog are provided. The starting and ending residue numbers refer to the positions of the first and last amino acids shown in the sequence. The putative PP1-binding motif is highlighted in bold.