Table 1: Medical treatment options for premature ejaculation [58].
| Therapy type | Drug | Trade name | Dose | IELT fold increase |
|---|---|---|---|---|
| Topical therapy | Lidocaine/prilocaine cream [29] | EMLA® cream | 25 mg/gm lidocaine, 25 mg/gm prilocaine | 4-6 |
| Oral therapy | Dapoxetine [35,49,31,39] | Priligy® | 30-60 mg on demand | 2.5-3 |
| Oral therapy | Clomipramine [30,34,38] | Anafranil® | 12.5-50 mg/day or 12.5-50 mg on demand | 6 4 |
| Oral therapy | Fluoxetine [56,64,23,66–68] | Prozac®, Sarafem® | 20-40 mg/day | 5 |
| Oral therapy | Paroxetine [36–38,60] | Paxil®, Seroxat® | 10-40 mg/day or 10-40 mg/day on demand | 8 1.4 |
| Oral therapy | Sertraline [59,64,61-66] | Zoloft® | 50-200 mg/day | 5 |
| Oral therapy | Citalopram [67–68] | Celexa®, Cipramil® | 20-40 mg/day | 2 |
| Oral therapy | Tramadol [69] | Zertane® | 62 mg ODT on demand or 89 mg ODT on demand | 2.4 2.5 |