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. Author manuscript; available in PMC: 2014 Jul 24.
Published in final edited form as: Proteins. 2014 Jul;82(7):1210–1218. doi: 10.1002/prot.24485

Figure 1.

Figure 1

Sequence alignment and phylogeny of selected ACPs and PCPs. (A) Secondary structure of BlmI is depicted above a sequence alignment. Below is the relative accessible surface area of each residue; white are buried residues, cyan are intermediate, blue are accessible. Completely conserved residues are highlighted with a red background and similar residues are colored red. Alignment created with MUSCLE43 and rendered with ESPript.44 (B) Phylogenetic tree revealing BlmI clades with PCPs. The ACPs clade together, and are marked with a bracket. Phylogeny created using the neighbor-joining method and rendered with MEGA5.45 PCP or ACP abbreviation (NCBI accession): BlmI (AAD42077), BlmIII (AAG02365), BlmIV (AAG02364), BlmV (AAG02360), BlmVI (AAG02359), BlmVII (AAG02358), BlmVIII (AAG02357), BlmIX (AAG02356), BlmX (AAG02355), ZbmI (ACG60769), ZbmIII (ACG60771), ZbmIV (ACG60772), ZbmV (ACG60775), ZbmVI (ACG60776), ZbmVIIa (ACG60777), ZbmVIIb (ACG60778), ZbmVIII (ACG60781), ZbmIX (ACG60773), ZbmX (ACG60782), TlmI (ABL74952), TlmIII (ABL74946), TlmIV (ABL74945), TlmV (ABL74941), TlmVI (ABL74940), TlmVII (ABL74939), TlmVIII (ABL74938), TlmIX (ABL74937), TlmX (ABL74936), TycA (AAC45928), TycB (AAC45929), TycC (AAC45930), SrfA-C (CAA49818), SgcC2 (AAL06679), KedY2 (AFV52209), MdpC2 (ABY66003), SpoT2 (ABP55169), EntF (AAC73696), EntB (AAC73687), DltC (AAB17659), PA1221 (AAG04610), EryAI (AAV51820), EryAII (AAV51821), EryAIII (AAV51822), FrenN (AAC18109), otcACP(AAA03334), actACP (CAC44202), ScACP (CAA60201), BsACP (CAB13465), EcACP (AAC74178), CalE8 (AAM94794), DynE8 (AAN79725), and SgcE (AAL06699).