Table 1. Synaptic coverage on neurons without ensheathing microglia.
Treatment |
Neuronal diameter |
Number of synapses per neuron | Average length of active zones (μm) | |
---|---|---|---|---|
Major axis | Minor axis | |||
PBS (n=15) | 13.45±2.37 | 10.55±2.28 | 5.53±1.13 | 0.96±0.17 |
LPS (n=15) | 13.02±2.11 | 10.15±1.19 | 5.73±0.80 | 1.02±0.20 |
P-value | 0.607 | 0.554 | 0.579 | 0.393 |
LPS, lipopolysaccharide.
Mean±s.d.; t-test.
Major axis: the height of the pyramidal cell profile, which approximates a prolate spheroid; minor axis: the width of the pyramidal cell profile.