Figure 6. Effect of wall shear rate on thrombus formation on microspot surfaces.
Whole blood was perfused over surfaces with or without vWF at indicated wall shear rates. (a) Measured parameters of thrombus formation at 1,600 s−1 (2 × 18 surfaces, clustering order as in Fig. 4). (b) Measurement parameters of thrombus formation at 150 s−1. (c) Linear subtraction heatmap of outcome parameters at low shear rate compared with high shear rate. P<0.01 (two-tailed Student’s t-test).