Figure 3. Conservation of RNA editing in mammalian Gabra3 transcripts.
The predicted topology for the α3-subunit of the GABAA receptor is shown with the position of the editing-dependent amino acid alteration (I/M site) immediately adjacent to the extracellular transmembrane 2/3 linker. Nucleotide and predicted amino acid sequence alignments between Gabra3 genomic and mRNA from several mammalian species are shown with the positions of the I/M editing site presented with inverse lettering.