Table 1.
Effects of metoprolol treatment on Th1/Th2 cytokines (Study II).
| Th1 | Th2 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| IL-1β (pg/mL) | IL-2 (pg/mL) | IL-12 total (pg/mL) | IFN-γ (pg/mL) | TNFα (pg/mL) | CXCL1 (pg/mL) | IL-4 (pg/mL) | IL-5 (pg/mL) | IL-10 (pg/mL) | |
| Control | 4.8 ± 0.2 | 7.8 ± 0.5 | 3016 ± 106 | 4.0 ± 1.0 | 1.6 ± 0.1 | 241 ± 18 | 7.8 ± 1.7 | 7.2 ± 0.8 | 81.8 ± 14 |
| Metoprolol | 4.9 ± 0.5 | 21.3 ± 14 | 2904 ± 95 | 5.9 ± 3.3 | 1.1 ± 0.1 | 161 ± 18 | 13.0 ± 7.4 | 8.0 ± 1.7 | 121 ± 52 |
|
| |||||||||
| P value (Mann-Whitney) | 0.712 | 0.538 | 0.389 | 0.735 | 0.008 | 0.005 | 0.601 | 0.951 | 1.000 |
Serum cytokine concentrations (pg/mL) were analyzed with the Mann-Whitney U test. Data are expressed as mean ± SEM. P < 0.01 was considered statistically significant.