Table 1.
Major clinical, lab, and imaging findings.
(1) Rapid progressive right hip destructive arthritis | |
(2) Morning stiffness greater than 1 hour | |
(3) Maximum active joint count of 11 | |
(4) Chronic metatarsal phalangeal joints arthritis with erosions, periarticular osteopenia on imaging of hands | |
(5) Right knee arthritis with no imaging evidence of crystal arthropathy | |
(6) Erythrocyte sedimentation rate (ESR) of 56 mm/h and C-reactive protein (CRP) 106.4 mg/L, antinuclear antibody (ANA) was weakly positive at 1:80, with a negative rheumatoid factor (RF), anticitrullinated peptide (anti-CCP), antidouble stranded DNA (anti-dsDNA), and extractable nuclear antigen (ENA) screen | |
(7) Two incidental pulmonary nodules | |
(8) A soft tissue calcified mass in the right sacroiliac (SI) fossa and right gluteal muscles | |
(9) Presence of extracellular calcium pyrophosphate dehydrate (CPPD) crystals in right hip joint, negative synovial biopsy for crystals | |
(10) Biopsy showed chronic inflammation, fibrosis, multinucleated giant cell reaction with dystrophic calcification, and reactive synovial proliferation |