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. Author manuscript; available in PMC: 2015 May 21.
Published in final edited form as: Neuron. 2014 May 21;82(4):809–821. doi: 10.1016/j.neuron.2014.04.002

Figure 8. Switching Regulation Rates in the Same Cell Can Preserve Specific Properties.

Figure 8

(A) Conductance regulation in a bursting pacemaker neuron. Membrane potential traces (500 ms duration) are shown at steady state, at the onset of a perturbation (hyperpolarizing leak), and at steady state following perturbation. Arrowheads above the rightmost trace indicate burst onset times of the unperturbed neuron, aligned to the first burst.

(B) Evolution of the same model as (A), but with regulation rule switched prior to the onset of the perturbation. Regulation time constants following the switch were chosen to preserve burst duration (see Experimental Procedures). Arrowheads as in (A). Membrane potential trace durations: 500 ms.