Skip to main content
. Author manuscript; available in PMC: 2014 Jul 24.
Published in final edited form as: Kidney Int. 2009 Nov 18;77(7):571–580. doi: 10.1038/ki.2009.424

Figure 3. Induction of cathepsin L in podocytes precedes FP effacement and proteinuria.

Figure 3

Upon an insult, stationary podocytes upregulate cytoplasm cytosolic cathepsin L expression and activity and develop motile podocyte foot processes (FPs). This migratory response leads to FP effacement, slit diaphragm remodeling, and proteinuria.58