Table 1.
Comparison of human orthologs of changed proteins with urine, plasma and kidney origin proteome
Corresponding human protein ID | Protein name | Plasma proteome | Urine proteome | Kidney origin proteome | Stable protein | Candidate biomarkers of diseases |
---|---|---|---|---|---|---|
P01009 |
Alpha-1-antiproteinase |
Yes |
Yes |
Yes |
Yes |
FSGS [22] |
P43652 |
Afamin |
Yes |
Yes |
Yes |
Yes |
Diabetic nephropathy [23] |
P02768 |
Serum albumin |
Yes |
Yes |
Yes |
Yes |
Adriamycin nephropathy mice model [24] |
P00450 |
Ceruloplasmin |
Yes |
Yes |
Yes |
Yes |
Diabetic nephropathy [25] |
P01042 |
Kininogen-1 |
Yes |
Yes |
Yes |
Yes |
Adriamycin nephropathy rat model [26] |
P02787 |
Serotransferrin |
Yes |
Yes |
Yes |
Yes |
Adriamycin nephropathy mice model [24] |
P23141 |
Carboxylesterase 1 |
Yes |
Yes |
No |
No |
None |
P01861 |
Ig gamma-4 chain C region |
Yes |
Yes |
No |
No |
Kidney calculi [27] |
P00747 |
Plasminogen |
Yes |
Yes |
No |
Yes |
Acute appendicitis [28] |
P02765 |
Alpha-2-HS-glycoprotein |
Yes |
Yes |
Yes |
Yes |
Diabetic nephropathy [23] |
P02760 |
Protein AMBP |
Yes |
Yes |
Yes |
Yes |
FSGS [22] |
Q96D42 |
T-cell immunoglobulin and mucin domain-containing protein 1 |
No |
No |
No |
No |
Renal cell carcinoma [29], acute renal failure [30] |
P19022 |
Cadherin-2 |
Yes |
Yes |
No |
Yes |
Ureteropelvic junction obstruction [31] |
Q6PID9 |
Aggrecan core protein |
No |
Yes |
No |
No |
None |
P00746 |
Complement factor D |
Yes |
Yes |
No |
No |
Dents disease [32] |
P02749 |
Beta-2-glycoprotein 1 |
Yes |
Yes |
No |
Yes |
Dents disease [32] |
Q13740 |
CD166 antigen |
Yes |
No |
No |
No |
None |
P06870 |
Kallikrein-1 |
No |
Yes |
No |
Yes |
None |
P61769 |
Beta-2-microglobulin |
Yes |
Yes |
Yes |
Yes |
Renal Interstitial Inflammation [33] |
Q9UGM5 | Fetuin-B | Yes | Yes | Yes | No | None |